CrystFEL is a suite of programs for processing Bragg diffraction data acquired with a free electron laser in a “serial” manner. Some of the particular characteristics of such data which call for a specialised software suite are:
- Each crystal is used for only one exposure, and there is no oscillation, rotation nor a large bandwidth or divergence. Therefore, many or all reflections are partially integrated.
- The crystals might be very small and the illumination highly coherent, leading to significant Fourier truncation effects on the detector.
- Many patterns, numbering tens of thousands or more, are required, so high throughput automated processing is important.
- The crystal orientations in each pattern are random and uncorrelated, which leads to special considerations during scaling and merging.