PhD supervisor: Prof. Richard Neutze
SO = Scientific Objectives;
TO = Training Objectives.
SO1: Observe structural changes in terminal oxidases using time-resolved WAXS and SFX.
SO2: Observe structural changes in rhodopsins using ultrafast WAXS and SFX.
TO1: Training in membrane protein biochemistry, purification and crystallisation.
TO2: Training in the use of state-of-the art X-ray sources.
TO3: Training in scientific computing software development.
Purifying membrane protein and growing membrane protein microcrystals of bacterial rhodopsins and terminal oxidases. The ESR will participate in both time-resolved WAXS and diffraction studies at synchrotron radiation sources and X-ray free electron laser, be educated in the tools of X-ray scattering and X-ray diffraction analysis, and develop code for the interpretation of structural changes using both methods.
Involvement with other tasks: Assist others with the development of tools for membrane protein crystallisation and nano-crystallisation, and with diffraction data analysis from nano-crystals.
Local Training: This ESR will be enrolled as a PhD student at the University of Gothenburg where many courses are given in English (structural biology, protein engineering, computing etc.).
2011 – 2014 – Integrated Masters, MBiol in Biochemistry, University of Leeds
2005 – 2011 – St Edwards School, Oxford. International Baccalaureate
MBiol Project: “Revealing asymmetry in single stranded RNA virus particles using Cryo-Electron Microscopy” in the Ranson Lab at the University of Leeds.
Internship at Research Complex at Harwell in DySS Lab:
Project 1: Developing a goniometer for single molecule spectroscopy.
Project 2: Small molecule synthesis and crystallization.